Spiramycin is an antibiotic belonging to the macrolide class and is isolated from cultures of Streptomyces ambofaciens. Side effects Spiramycin can induce various types of side effects, although not all patients experience them. This depends on the different sensitivity that each person has towards the drug. Therefore, it is not certain that all undesirable effects…
Daptomycin is a cyclic lipopeptide of natural origin and with antibiotic action, obtained by fermentation from Streptomyces roseosporus. It has a spectrum of action restricted especially to Gram-positive bacteria and exerts a bactericidal antibiotic action (i.e. it is capable of killing bacterial cells). Warnings In patients with kidney disease, the doctor may decide to administer…
Erythromycin is a drug with antibiotic action and is considered the progenitor of the macrolide class. It was obtained for the first time from crops of Streptomyces erythraeus. Erythromycin – Chemical Structure Erythromycin has a bacteriostatic antibiotic action, i.e. it does not kill bacterial cells but inhibits their growth. Directions What is it used…
Ertapenem is a beta-lactam antibiotic belonging to the carbapenem class. It is mainly used for the treatment of infections caused by anaerobic bacteria and has a certain resistance towards beta-lactamases (enzymes produced by bacterial species that hydrolyze the beta-lactam ring of the antibiotic, thus making it inactive). Ertapenem – Chemical Structure Furthermore, ertapenem has…
Generality What is Fosfomycin and what General Characteristics Fosfomycin is an active ingredient antibiotic action having natural origin obtained for the first time from crops of Streptomyces fradiae. Fosfomycin can be administered both for oral route (in the form of granules for oral solution) and intravenously (in powder form for solution for infusion). Fosfomycin-based medicines…
Imipenem is a drug with antibiotic action of the beta-lactam type, belonging to the carbapenem class. It is important to know that imipenem is never administered alone, but is marketed in pharmaceutical formulations in which it is found in association with cilastatin. Cilastatin is an inhibitor of dehydropeptidase-1, an enzyme capable of hydrolyzing the beta-lactam…
Definition and Examples of Lantibiotics The term lantibiotics refers to antibacterial substances synthesized by particular lactic bacteria. These microorganisms produce lantibiotics to prevent pathogens from settling in the same environment and taking away their nourishment. In the past, antibiotics with a broad spectrum of action have been studied and researched, therefore active against all bacterial…
What is Linezolid and what general characteristics? Linezolid is an active ingredient synthetic antibacterial belonging to a new class of antimicrobials, that of oxazolidinones. Available in various medicines for oral and parenteral administration, linezolid is used to treat infections caused by Gram-positive bacteria and anaerobic microorganisms. Oral medicines containing linezolid can only be sold upon…
What are Macrolides? Macrolides constitute a class of antibiotics of natural origin. The progenitor of this class is the erythromycin obtained from crops of Streptomyces erythraeus. Macrolides – or macrolide antibiotics – owe their name to the large lactone ring (from a chemical point of view, it is a cyclic ester) that characterizes their chemical…
Meropenem is a beta-lactam antibiotic belonging to the carbapenem class. It is a synthetic drug that – compared to imipenem (another antibiotic belonging to the carbapenem class) – has a broader spectrum of action and a certain resistance towards beta-lactamases (particular enzymes produced by some bacterial species whose function is to hydrolyze the beta-lactam ring,…
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